Brittle Diabetes

Self-monitoring of blood glucose (SMBG) methods have made it possible for most people with diabetes to check their blood glucose (sugar) levels regularly. Before SMBG became available, many people with diabetes were unable to control their blood glucose levels and regularly experienced brittle diabetes when blood glucose levels unpredictably swing between high and low levels. People with type 1 diabetes may be at a greater risk of having swings in their blood sugar levels than those with type 2 diabetes.

Since SMBG has become so common, most people with diabetes do not experience brittle diabetes. However, individuals who have intense reactions to stress, medications and food still may experience brittle diabetes. Even with regular eating and insulin schedules, some individuals still may have uncontrollable blood swings from one day to the next.

You may find it difficult to determine why these extreme changes in your blood glucose levels are occurring. Like every puzzle, there are several pieces you may need to fit together before you get a clear picture of why this is happening. According to the American Diabetes Association, many factors may cause such dramatic changes in blood glucose levels, including stress hormones, food absorption and the insulin absorption.


Brittle Diabetes
Brittle Diabetes

If you’re experiencing uncontrollable swings in your blood glucose levels, and you’re confused about why this is happening, ask yourself the following:

  • Do you allow enough time for your insulin to begin working before you start eating?
  • Are you measuring your insulin dose correctly? If a single dose is too large, insulin action times may differ from day to day.
  • Do you rotate your injection sites regularly? Rotating your injection sites regularly keeps your skin healthy and may help insulin absorption. Also, consider using the abdomen as your injections site because it may provide the most consistent insulin absorption rate.
  • Each time you inject insulin, do you inject it at the same depth? “Intramuscular (in the muscle) injections are absorbed more rapidly than subcutaneous (beneath the skin) injections.”
  • Do you inject insulin into muscles that get a lot of use? If you inject insulin into a muscle that gets a lot of use, quicker insulin absorption may occur.
  • What are the temperatures of your home and workplace? Warm temperatures speed up insulin absorption, and cold temperatures slow down insulin absorption.
  • Do you smoke? Smoking tobacco slows down insulin absorption.
  • Do you experience hypoglycemia (low blood sugar) frequently? If so, your liver releases glucose as a natural defense, which may interfere with your insulin’s job.
  • Do you experience long periods of hyperglycemia (high blood sugar)? If so, you may become dehydrated. As a result, it may be more difficult for your body to absorb insulin.
  • Do you have neuropathy (nerve damage)? Neuropathy may cause diarrhea or slow down the digestion of food, affecting your blood glucose levels.

Since many factors affect your blood sugar levels and insulin absorption, the answers to these questions may help you avoid brittle diabetes unpredictable blood glucose swings.

More about Diabetes: DiabetaZone | Diabetic Diseases

Finasteride, Good or Bad Treatment Option?

Over 10 years ago at a dermatology congress in Sydney, Australia Kieth Kaufman and colleagues presented a study done with over 1,800 men aged 18-41 with stage 2 or higher androgenic alopecia. The men were treated with Finasteride (Propecia) during a 12 month period. The study revealed that baseline hair counts increased significantly while the placebo groups hair counts continued to be lower. This study was perhaps the first to clearly demonstrate the positive effects of Finasteride in people suffering from hair loss. There have been multiple studies since then, all with beneficial results. Of the side effects found, the most common was decreased libido found in 1-8% of patients. Erectile dysfunction was more common in the treatment group vs the placebo group (1.3% vs 0.7%).

Finasteride is also one of the most commonly used treatment options for benign prostatic hyperplasia (BPH) due to the common physiopathology between androgenic alopecia and BPH. An article published in 2003 performed at the University of Texas Health Science Center in San Antonio showed that the use of Finasteride prevents or delays the appearance of prostate cancer by 24.8%. The study included over 18,000 men over 55 years of age who were assigned Finasteride 5mg or placebo during a 7 year period. The overall incidence of prostate cancer after the 7 year period was 18% in the Finasteride group, compared to 24% in the placebo group.

Finasteride has been approved for the treatment of androgenic hair loss and is attractive because it inhibits the conversion of testosterone to its more potent form dihydrotestosterone inside the prostate. According to the authors of the study, the greater reduction in risk of prostate cancer incidence must be weighed against the smaller sexual side effects encountered.

Finasteride, good or bad treatment option

The use of 5mg/day of Finasteride (Proscar) for BPH is known to lower serum concentrations of Prostate Specific Antigen (PSA). PSA is used to measure prostate activity and risk of prostate cancer.

A randomized controlled trial published in Lancet Oncology in 2007 aimed to assess the effect of Finasteride 1mg/day (Propecia) and its effect on PSA serum levels. Over 350 men aged 40 to 60 with androgenic hair loss were enrolled in the study and assigned 1mg/day of Finasteride and followed during a 48 week period. The results showed a median PSA level decrease of 40% in the Finasteride group compared to a 0% difference for the placebo group.

The study concluded that in men 40 to 60 years of age with 1mg/day of Finasteride during a 48 week period lowers PSA.

Does Ketoconazole Shampoo Work for Hair Loss?

There are hundreds, perhaps thousands of shampoo based treatments that claim produce hair growth. It is difficult to assess all of them and generalize them. Many ingredients are herbal such as He Shou Wu or Saw Palmetto, others contain chemical ingredients such as minoxidil (Rogaine), others are based on vitamins and minerals, and some even include antibiotics such as Ketoconazole. Each shampoo formula is unique and has different effects. While many substances have been studied, it is impossible to perform clinical trials on all the herbal and vitamin based products that become available.

A study was performed in Belgium and published in the prestigious Journal of Dermatology which measured the long term effects of Ketoconazole in Androgenic Alopecia. The study claims that genetic predisposition and the influence of androgens are beyond doubt, however they do not explain the presence of inflammatory cells on the transitional hair follicles. Histological observations show that there is a significant number of inflammatory cells on the hair follicle stem cells. This study enrolled a total of 39 men of which 27 were assigned to an exclusive Ketoconazole 2% shampoo (Nizoral), while 12 men used an unmedicated wash and go shampoo (Vidal Sassoon) with or without Minoxidil (Rogaine).

Ketoconazole is a well-known antifungal drug that is used to treat and prevent fungal skin infections. Commercially it is available as an antidandruff shampoo, topical cream, or in tablets. It is known to produce a certain anti-inflammatory effect. It has been tested in androgenic alopecia because it is active against Malassezia spp and Staphylococcus spp which are part of the scalp microflora.

Ketoconazole Shampoo for Hair Loss
Ketoconazole Shampoo for Hair Loss

This study concluded that there’s an unequivocable effect of a 2% Ketoconazole shampoo on hair follicles affected by Androgenic Alopecia. Hair density, size, and proportion of anagen follicles were all improved compared with the control group. The study concludes that the regular use of 2% Ketoconazole shampoo may participate to improve the presentation of Androgenic Alopecia. There was a significant reduction in inflammatory cells. Although the studies results are encouraging, it is noted that a further controlled study is necessary to confirm the findings in a larger group of patients.

More recent studies suggest that Ketoconazole has anti-inflammatory properties that can mend skin damage caused by Androgenic Alopecia, disrupt the production of dihydrotestosterone (DHT), and may even have a stimulating effect on hair growth.

That’s about chemical treatment for hair loss or a stimulating hair growth. If you looking for hair treatment with natural methods please visit a good article about best hair loss treatment in 2018 blog.

Diet for Diabetics

How to Diet for Diabetics Who Secured the Super Potent
How to Diet for Diabetics who are also often referred to as DM, diabetes, and diabetes forced the sufferer to run healthy life pattern so that blood sugar levels can be in control while simultaneously preventing further complications. People who are at risk or have a diagnosis of diabetes can still live with normal as long as it remains to live true life patterns on a regular basis. You also do not always have to rely on drugs namely by following a diabetic diet will complete review here.

Diet for Diabetics

For those of you who suffer from diabetes or diabetes but would like to go on a diet to get the ideal weight but not causing the new disease, you need to follow the following ways:
1. Consumption of high fiber Foods and carbohydrates
Carbohydrates can indeed deliver a huge impact for diabetics, but by no means should avoid whole foods that contain carbohydrates but rather smarter in choosing the type of carbs what will be consumed.
Consume complex carbohydrates and high-fiber foods also contain indeed advisable, for two of these substances will be processed in long digestion while keeping the stability of blood sugar. (Read Also: White Water Diet Rules)
Complex carbohydrates are also a source of energy for the body so that hunger could come for longer. Note the limitation in consuming pasta, rice, the food contains excess sugar, alcoholsodas, and snacks also. Food and drink the better replaced with foods containing wheat as wheat bread, red rice and cereal are also very high in fiber content and high nutritional value.
In addition to carbohydrates, the consumption of fresh fruits and vegetables more because of good nutrition can be obtained from different types of vegetables needed diabetics such as spinach and broccoli. While for the recommended fruits for diabetics are peaches, apples, berries, tomatoespear and noni fruit is also a good is consumed directly or made into juice without the extra sugar. Noni fruit has proven deposits of even porxeronin can improve the function of the liver or pancreas in producing insulin so it is very good for sufferers of diabetes. (Read Also: Diet Low Protein)
2. More Jelly With Sweet Intake
How to diet to do diabetics do not mean avoiding the use of sugar entirely, but to note is packed with enough portion and not excessive. Is a jelly with the sweet intake is consuming food or drink is sweet on a time clock to eat as a dessert and then no longer consuming snacks or snack outside of the hours of the meal?
In addition, the lower portion of the main food if afterward want to eat sweet desserts, because the intake of sweet that will be eaten afterward also contain carbohydrates.